In the near future, a Virtual Reality Massive Multiplayer Online Role-Playing Game (VRMMORPG) called Sword Art Online has been released where players control their avatars with their bodies using a piece of technology called Nerve Gear. One day, players discover they cannot log out, as the game creator is holding them captive unless they reach the 100th floor of the game's tower and defeat the final boss. However, if they die in the game, they die in real life. Their struggle for survival starts now...

Rakuro Hizutome only cares about one thing: beating crappy VR games. He devotes his entire life to these buggy games and could clear them all in his sleep. One day, he decides to challenge himself and play a popular god-tier game called Shangri-La Frontier. But he quickly learns just how difficult it is. Will his expert skills be enough to uncover its hidden secrets?

Kojou Akatsuki's days as an ordinary high school student in the Demon District of Itogami Island come to an abrupt end after a fateful encounter leaves him with the remarkable abilities of a vampire. It isn't long before he is thrust into the center of attention when it is discovered that he is the fourth primogenitor, an immensely powerful vampire whom most consider to be merely a legend. Fearing Kojou's destructive potential, the Lion King Organization sends in an apprentice sword-shaman, Yukina Himeragi, to monitor, and should he become a threat, kill the boy deemed the world's most powerful vampire. Forced together by circumstance, the two form an unlikely alliance as Kojou comes to terms with his abilities and they both struggle to protect the city from various emerging chaotic forces.

Lloyd is a white mage who was unexpectedly banished from the hero's party. As he was lost and uncertain, he happened to cross paths with an S-rank adventurer party in need of a white mage, so he joined them on their quest. Little did anyone know at the time that the hero's party would fall apart and Lloyd would rise to fame.

After being turned into a cyborg, Kisaragi faces pursuit from vampires and vengeful yakuza.